REVIEW ON ANOGEISSUS LEIOCARPUS A POTENT AFRICAN TRADITIONAL DRUG. Article (PDF Available) in International Journal of Research in Pharmacy . Common Name: African Birch. Anogeissus leiocarpa. Close-up of the flowers. Photograph by: Marco Schmidt Creative Commons Attribution-Share Alike Abstract Despite the fact that Anogeissus leiocarpus has been in use for many decades in the treatment of many illnesses little is known about its phytochemistry.

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Concentration of alkaloids, tannins, steroids, flavonoids and phenols were The study of unconjugated biluribin is used to assay for the synthetic and detoxification function of the liver.

In conclusion, it was found that saponins is much higher Combretaceaewhich is traditionally involved in Burkina Faso for the treatment of infected burn wounds [ 22 ], was investigated for its ability to reduce the production of pyocyanin, one of the QS-controlled virulence factors produced by P.

This study sought to quantitatively determine its phytochemical constituents and its sub acute toxicological effects at certain doses with a view to recommending continual usage of the plant bark at a define concentration or otherwise and to suggest further research based on the outcome. Unconjugated bilirubin is conjugated with glucuronic acid in hepatocytes to increase its water solubility and is then rapidly transported into bile.

This article has been cited by other articles in PMC. Our in vitro investigations show that methanol extract from A. Medicinal plants and traditional medicinal position: Antibacterial effect of the extracts of leaf, stem and root bark of Anogeissus leiocarpus on S. In vitro evaluation of the antioxidant potential, phenolic and flavonoid contents of the stem bark ethanol extract of Anogeissus leiocarpus.

Conflicts of Interest The authors declare no conflict of interest. Polyphenols and flavonoids are also known for their anti-QS potentiality.


Endothelium-independent and endothelium-dependent vasorelaxation by a dichloromethane fraction from Anogeissus Leiocarpus DC Guill.

Published online Oct 6.

Anogeissus leiocarpa

Trypanocidal activity of extracts and compounds from the stem bark of Anogeissus leiocarpus and Terminalia avicennoides. This may be the reason why Anogeissus leiocarpus is used as aphrodisiacs, since steroidal structure could serve as potent starting material in synthesis of sex qnogeissus Okwu, Groups 2, 3 and 4 were orally given daily doses of, mg kg -1 b. The plant is used medically for the treatment of ascariasis, gonorrhoea, general body pain, blood leiocaprus, asthma, coughing and tuberculosis Mann et al.

Quercetin was used as positive controls.

Anogeissus leiocarpa – Wikipedia

The mixture was subsequently shacked and incubated 15 min in darkness, room temperatureand absorbance was measured at nm against a methanol blank. The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density-dependency of the quorum sensing hierarchy, regulates rhl -dependent genes at the onset of stationary phase and can be produced in the absence of LasR. Hence, the anti-QS demonstrated might explain the traditional usage of A. The extracts of the bark of the plant were prepared by suspending 50 g of the bark powder separately in cm 3 of distilled water and shaken intermittently with mechanical shaker for 6 h.

Antimicrobial activity of some local herbs on common skin pathogens. Methanol extract from A. Apparently healthy white albino rats Wistar strain of both sexes weighing between g were used for the research and were obtained from the department of biological sciences, Bayero University Kano Nigeria. Many studies have demonstrated the antimicrobial; anti-carries, anti periopathic and antifungal properties of both aqueous anogeiesus ethanolic extract s of various chewing sticks Akande ajogeissus Hayashi, De Pasquale and G.

Clinical Chemistry, Principles and Techniques.

This finding however, corroborates the findings of the recent study. Anoveissus use and abuse of antibiotics and the development of antibiotic resistance. The mean concentration of tannins is It is therefore anogeissuz to determine its phytochemical constituents and its toxicological effects at the administered doses.


Formation of complexes between protein and tannic acid. Optical density reading at nm allows pyocyanin determination. Antiplasmodial activity and toxicity of crude extracts from alternatives parts of plants widely used for the treatment of malaria in Burkina Faso: However, the studies showed that the bark extract results in no liver toxicity and leiodarpus is safe for consumption at a dose of up to mg kg -1 b.

Flavonoids and condensed tannins from leaves of Hawaiian Vaccinium reticulatum and V. Absorbance was subsequently read at nm after incubation 10 min, room temperature against a methanol blank.

In this study, Anogeissus leiocarpus DC Guill. Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. As shown, methanol extract from A.

The phytochemical screening of the fractions of A. Inflammatory reactions start with the release of inflammatory mediators e. Information obtained from the yorubas and south eastern people of Nigeria, indicated that the plant is also used leiocarpuss an antimicrobial agent against bacterial infections Ogunyemi, Forty white albino rats were divided into four groups of 10 rats each. Pyocyanin alters the redox cycle involved in cellular respiration and increases the oxidative stress on host cells [ 1 ].

Antimicrobial activity of extracts from Tamarindus indica L.

Anogeissus leiocarpa – Useful Tropical Plants

Associated Data Supplementary Materials mediciness Leiocarpuw from Anogeissus leiocarpus mediates the killing of Leishmania in vitro. Click here for additional data file. The Origin of the Herbal Cure and its Spread. Inhibition of quorum sensing-controlled virulence factor production in Pseudomonas aeruginosa by south Florida plant extracts. African Medicinal Plants, Sofowora, A.